6. With new variants of SARS-CoV-2 emerging, the COVID-19 pandemic is . Looks like part of my theories is debunkable - one of the authors did think to check IL-6 and IL-6R before and after exercise in CFS patients (good on him) and found no differences between them and the controls, although he did find "F(2)-isoprostanes were higher (P<0.05) in CFS patients at rest and this difference persisted immediately and 24 h post-exercise." They were ahead of their time back then. Wormwood. Suramin (suramin hexasodium; CI-1003) is a polysulfonated naphthylurea. Nattokinase (proteolytic enzyme) has a history of being used to, Giant Hyssop or Horsemint (Agastache urtifolia), Wheatgrass and Wheatgrass Juice (the young blades). Im sorry but I cannot say exactly how much is required for the reversal of autism. A small, FDA-approved phase 1 clinical trial in 2017 tested suramin's effect on certain "core" autism symptoms in five boys, as compared with five boys given a placebo. The Eastern White Pine (. It also has an, Trypan blue is so-called because it can kill trypanosomes, the parasites that cause sleeping sickness. Thanks for being part of this journey with me. It is only available by injection, and has been a closely guarded secret not made openly . A drug discovered more than 100 years ago may hold the key to combating autism symptoms, according to a study. No Carter, not really. Having said that, we can do a lot more about it than simply sitting around and waiting to see who is harmed or dies. I dont particularly like the taste of Green Tea either, but when I infuse it together with Rooibos Tea its a wonderful drink. This has me very excited. National Library of Medicine. If you dont like something one way, do something else with it until it becomes acceptable. But people of today seem to think they can consume anything they like and they dont expect that it will make them sick! By facilitating the exit from the arrested mitochondrial progression needed to complete the healing cycle, recovery from chronic illnesses currently considered incurable may one day be possible. It likes to be on the cold side of the mountain and doesnt do well on the warmer side. [2], It is unknown whether it is safe for the baby when a woman takes it while breastfeeding. Naviaux Lab, 2023. No I am not sure if they need to be heated for the Suramin to be released. Of-course there are others but you do need to do your own research concerning the types of pines in your area. We were lucky that suramin is a non-selective inhibitor of most of the known types of purinergic receptors. "Suramin inhibition of growth factor receptor binding and mitogenicity in AKR2B cells. Its considered almost a pest in New Zealand as its everywhere. I was desperate, and I gave her one capsule, 150mg, of Sytrinol. Suramin does not cross the bloo Treatment of late-stage human African trypanosomiasis is complicated by the presence of trypanosomes within the central nervous system (CNS). [3] In regions of the world where the disease is common suramin is provided for free by the World Health Organization (WHO). Ph-D Boric Vaginal Suppositories 36 Count Each Exp 10/23. Suramin can be found in trees, plants and spices which may be growing even in your front lawn! I'm not too concerned about Il-6 being a problem in CFS but I've thought about that receptor a bit. I'm fascinated and excited by this new research on cell danger response (CDR): Low-dose suramin in autism spectrum disorder: a small, phase I/II, randomized clinical trial abstract and the ramifications for autism as well as anxiety and other chronic health conditions. y puede cancelar su suscripcin en cualquier momento. It is a growth factor antagonist for palliative treatment in hormone-refractory prostate cancer and hormone-responsive metastatic prostate cancer.. Purpose. "Suramin: a novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer. ", 9. Thank you for pointing that out. Regarding our own experiment with natural antipurinergic therapy, we've been trialing Kudzu for the past three weeks and the outcome has been pretty impressive. She discusses suramin and pine needles, corruption surrounding that, and gives many more suggestions: !function(r,u,m,b,l,e){r._Rumble=b,r[b]||(r[b]=function(){(r[b]._=r[b]._||[]).push(arguments);if(r[b]._.length==1){l=u.createElement(m),e=u.getElementsByTagName(m)[0],l.async=1,l.src="https://rumble.com/embedJS/u4"+(arguments[1].video?'. Jason Shurka was interviewing Dr Judy Mikovits PhD., and he asked the leading question: Do you know of any way, to heal oneself from the injuries from the current injection? Research is already being hurriedly done in that direction in the hope that many lives can be saved and much severe illness avoided. COVID-19 pandemic. Pine Trees are widely available throughout the world and make an amazing tea high in vitamin C and A. My high quality source was, of course, wikipedia, but here are some better ones. The algorithms are set to make it hard for me to be seen there If you want to stay connected, here is one way. I haven't seen night awake or silly giggling in the middle of the night since he started Kudzu. https://www.biorxiv.org/content/10.1101/2020.10.06.328336v1, 3. It is our hope that each success will lay the groundwork for more successes, and soon there will be a drug, device, and therapeutic Renaissance that will create dozens of new tools that doctors can use to regulate the cell danger response and help patients heal. Antiviral Research 121, 39-46. This has the effect of blocking downstream G protein mediated signaling of various GPCR proteins including rhodopsin, the A1 adenosine receptor, the D2 receptor,[19] the P2 receptor,[20][21] and ryanodine receptors. Brown-colored suramin should not be used. "Understanding the mechanism of the antimitogenic activity of suramin. Myers, Charles, Michael Cooper, Cy Stein, Renato LaRocca, M. M. Walther, Gary Weiss, Peter Choyke, Nancy Dawson, Seth Steinberg, and Margaret M. Uhrich. "Suramin binds to plateletderived growth factor and inhibits its biological activity. You must realise too that the medbeds are for good and not evil. Also, Suramin not only blocks P2X7 but also the related Pannexin 1 channel. ! Suramin and trypan blue were detected using scheduled multiple reaction monitoring (MRM) with a dwell time of 30 ms in negative mode and retention time window of 7.5-8.5 min for suramin and 8.4 . ", 16.Spigelman, Zachary, Amy Dowers, Susan Kennedy, Dennis DiSorbo, Michael O'Brien, Ronald Barr, and Ronald McCaffrey. Common side effects of suramin include shock, dizziness, fatigue, headache, loss of consciousness, peripheral nerve damage (neuropathy . If this works, it would literally be an answered prayer ! [6] In the United States it can be acquired from the Centers for Disease Control (CDC). It loves the cold, the colder the better. One important way that stress-triggered eATP is released occurs through pannexin 1 containing channels in the cell membrane. 3 (1985): 265-273. No medical research confirms this yet, but people have been using suramin for autism and as a powerful antiviral. A small study found that a 100-year-old drug called suramin, which is used to treat African sleeping sickness, showed promising results for treating autism spectrum disorder (ASD) symptoms in . Yin, W. et al. Albulescu, I.C., Kovacikova, K., Tas, A., Snijder, E.J., and van Hemert, M.J. (2017). The drug is still sold by Bayer under the brand name Germanin. God knew a time would come when if our passed-on grandparents or great-grandparents came back for a tour of our supermarkets, they wouldnt recognise half the food on the shelves! "Suramin: a novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer." "Suramin rapidly alters cellular tyrosine phosphorylation in prostate cancer cell lines." It is still early to say but maybe this will enter the top three interventions. Suramin further decreases the activities of a large number of enzymes involved in DNA and RNA synthesis and modification: DNA polymerases (103, 104), RNA polymerases (103, 105, 106), reverse transcriptase (18, 103), telomerase (67), and enzymes involved in winding/ unwinding of DNA (107, 108) are inhibited by suramin, as well as histone- and chromatin-modifying enzymes like chromobox proteins . Dr. Jennifer Danials Turpentine and sugar was a bit of a story about a Grand Mother had done for years. I have bought this before for myself just for good health. (2017) conducted a trial that studied the impact of a single dose of suramin in children with autism and compared their result to a group of children who received the placebo drug (Saline). & Naviaux, R.K. Optical phenotyping of human mitochondria in a biocavity laser. Some batches of suramin contain impurities that are brown in color. Funny how uridine is a p2y2 agonist and so many people take it as a nootropic. 2017-2023 Dr. James Odell, ND, OMD, L.Ac. He also talks about some other VERY interesting information that you have to hear for yourself And of course, a health disclaimer. Suramin may cause serious side effects. The simplest and most common of weeds are often the very medicine we need to counteract our ill health. De Clercq, Erik. Any natural medicine with 0.01% of these deaths and side effects would have been pulled from the market immediately. Kudzu is POSSIBLY SAFE for most people when taken by mouth appropriately for up to 4 months or when injected intravenously (by IV) for up to 20 days. 4 (1993): 701-710. Quercetin. Here are some certain foods that are known to contain Suramin and Shikimic Acid. Suramin is a medication used to treat African sleeping sickness and river blindness. Several P2Y12 inhibitors are approved to treat heart disease, but other purinergic receptors are likely to be more important in ASD. Journal of ethnopharmacology 35, no. 6 Natural Alternatives to Ivermectin with Herbs. LifeWave X39 and X49 Performance Bundle - 30 Patch. Upon treatment with suramin, median individual glycosome volume increased from 0.0113 to 0.0127 m3 (p 0.037). Once all the needles have sunk to the bottom and the tea has . Keep a list of all your medications with you, and share the list with your doctor and pharmacist. northwestern Africa and North America, is known . I was reading just yesterday about the Douglas Fir pine tree. The Naviaux Lab discovered that the unique properties of suramin made it the first in a new class of drugs that could be used to test the cell danger response (CDR) hypothesis for the origin and treatment of autism spectrum disorder (ASD). The active ingredients in wormwood are toxic to most types of intestinal worms, including Giardia lamblia, a parasite responsible for giardiasis. I hope that someone posts something here which will help. I love the fact that you are speaking from what you yourself did excellent! Bayer drug suramin is the antidote but it's only available to rich people in Europe. She was annoyed people were being told to make it. [22], Suramin was studied as a possible treatment for prostate cancer in a clinical trial. Sartor, Oliver, Catherine A. McLellan, Charles E. Myers, and M. M. Borner. "Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin. Curcumin was the active ingredient in an intravenous infusion that killed the patient of a California-licensed naturopathic doctor. It is not found in pine needles and cannot be found in any herbal teas. However, despite increased lipid solubility, alcohols with a molecular volume of > or = 46.1 ml/mol (1-butanol, 1-pentanol, trichloroethanol, and dichloroethanol) were without effect on the ATP-activated current. In addition, pharmaceutical grade suramin is hard to make. Roundup is not sprayed on lawns. We are doing this on a trial period to see if this interests our audience. However, it is imperative to choose the right pine needles as there are 20 known toxic varieties of pine trees. "Suramin binds to plateletderived growth factor and inhibits its biological activity." It is considered a ryanodine agent . Disclaimer: The information presented in this article and podcast are for informational purposes only. Descriptions. Some of the other P2X7 and P2Y2 inhibiting compounds listed at the bottom of. Because He knew that we would move far away from the foods He designed for us. Direct TNF inhibition through identification of potent small . [5] It is on the World Health Organization's List of Essential Medicines. Suramin is used in the treatment of African sleeping sickness (African trypanosomiasis) and river blindness (onchocerciasis), infections caused by parasites. But this so-called pest, this common pine tree, is packed full of goodness! ", 14.Stein, C. A., R. V. LaRocca, R. Thomas, N. McAtee, and Charles E. Myers. 1. For a better experience, please enable JavaScript in your browser before proceeding. ", 17.Kathir, Karuppanan Muthusamy, Thallapuranam Krishnaswamy S. Kumar, and Chin Yu. B-complex vitamins: The "complex" part is important. readily accessible. Taken together, the results show that sgp130 may exert an anti-inflammatory effect on microglia and neurons by inhibiting IL-6 binding. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. Other rare systemic effects include decreased blood pressure, fever, rapid heart rate, and convulsions. The study participants in question used 300 milligrams (mg) each day. PloS one 9, e91765-e91765. (3) This study also says suramin doesn't work well on p2x4. We envision a shelf-full of related drugs, a toolkit of devices, and a suite of new autonomic balancing, cognitive and behavioral therapies that can be matched to each patient and each disease. (2014). 3 (2006): 899-906, 18.https://pubchem.ncbi.nlm.nih.gov/compound/Suramin-sodium. the inhibitory effects of NhPV and Suramin were confirmed by the wild type SARS-CoV-2 (hCoV-19 . Suramin (as mentioned by Dr Judy Mikovits, PhD) and Shikimic acid are both found within the needles of the common pine tree. Today, 100 years later, it is being studied for a variety of applications and treatments . Suramin is manmade and is not a natural product found anywhere in Nature. An alternative to synthetic drugs is the search for anti-parasitic plant extracts or secondary metabolites derived from them. Proceedings of the National Academy of Sciences 83, no. Natural Protocol: This protocol may mitigate damage in those with "buyer's remorse" who've been injected with spike protein, graphene oxide, SM-102, and mRNA.The same protocol is very useful to protect those concerned with the spike protein transmission FROM those who've been injected.. Due to its anti-inflammatory properties, turmericspecifically curcumin, the main active ingredientmay be one of the top natural remedies showing promise for treatment and management of autism symptoms. The differences are about 20% higher. It is not found in pine needles and cannot be found in any herbal teas. [12], Suramin is not orally bioavailable and must be given intravenously. Thats my guess only. 100 Years of Suramin. Suramin as medication is used to treat African sleeping sickness and river blindness. so i do wonder what the one is behind Suramin. especially valuable as potential new sources for rapid responses against the ongoing 4! In other words perfect! A polyanionic compound with an unknown mechanism of action. @Jesse2233 but i think you are on the right track, as almost every medication is based on a "natural" supplement/herb. Suramin is used in the treatment of African sleeping sickness (African trypanosomiasis) and river blindness (onchocerciasis), infections caused by parasites. Most importantly the mysterious seizure-like episode has disappeared. I have heard of a study at UCSD using Suramin to treat autism. [2] Sore palms of the hands and soles of the feet, trouble seeing, fever, and abdominal pain may also occur. The all natural form of suramin might be licorice root, NAC,vitamin C , green tea. Are you aware of anything?. However. Try to put aside your previous teaching and open your spirit to receive from God. So if they sell their homewho knows. The exceptions to this are the P2Y12 inhibitors like Plavix, which inhibit ADP-stimulated platelet aggregation. 14.Stein, C. A., R. V. LaRocca, R. Thomas, N. McAtee, and Charles E. Myers. Hosang, Markus. Thank you!). However, even better than the medication known as Suramin, and one that does not produce all the adverse side effects that come with pharmaceutical drugs, perhaps Pine Needle Oil may serve as a natural silver bullet. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. So we picked dandelions and split the stems washed them and put them in vinegarsometimes eating them before they were fully pickled. Green tea research shows an amelioration of behavioral aberrations by a daily intake dose of the extract; doses range from 75 to 300 mg/kg after postnatal day 14 up to day 40 in animals with . "Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes. Ren, P., Zou, G., Bailly, B., Xu, S., Zeng, M., Chen, X., Shen, L., Zhang, Y., Guillon, P., Arenzana-Seisdedos, F., et al. The most effective dosage solution is the Pine Needle Tincture. 1! Dr. Daniels has now been using this and has no issues and I have been using it also. Suramin inhibits Zika virus replication by interfering with virus attachment and release of infectious particles. (See protocol below). Gourley, P.L. It is illegal to use suramin in humans for any purpose in the US except in FDA-approved clinical trials. It is given by injection into a vein.. Suramin causes a fair number of side effects. The regimen commonly prescribed to treat CNS-stage disease involves the use of the trypanocidal drugs suramin and melarsoprol. Maca Root 8050mg Per Caps, 4 Months' Supply Supports Reproductive Health Natural. Fragrance Oil 4 oz. The purpose of this website is to promote broad consumer understanding and knowledge of various health topics. Content may not be reproduced in any form. 11.Croci, R., Pezzullo, M., Tarantino, D., Milani, M., Tsay, S.-C., Sureshbabu, R., Tsai, Y.-J., Mastrangelo, E., Rohayem, J., Bolognesi, M., et al. Nothing present here is intended to diagnose or treat any disease, and there are no supplements or products offered for sale in relation to this information. Suramin successfully improved all the core symptoms of ASD and the metabolic and GI abnormalities in both animal models and a small human clinical trial. Thank you! Are You Sleeping in Scary, Toxic Contaminated Air? HUGE! It is also common to experience various sensations in the skin, from crawling or tingling sensations, tenderness of palms and the soles, and numbness of hands, arm, legs or feet. Douglas fir is ok, white pine is ok. Hi Marilyn [2] Severe side effects may include low blood pressure, decreased level of consciousness, kidney problems, and low blood cell levels. Weekly updates on the topics that matter the most to you! This antidote to the contagion, that has been known of by the upper levels of the medical establishment and insiders of the elitist class for almost 100 years, is called Suramin, an isolated compound originally derived from an extract of pine needle oil. "Antiproliferative effects of suramin on lymphoid cells. Im so thankful that we are entering into a whole new era. A vitamin B complex contains B6, B12, biotin, and folate, essential vitamins for the nervous system and can help with the formation of serotonin. I was reading just yesterday about the Douglas Fir pine tree. I did feel better with better health after I drank it myself. Usually after the 2nd fill I can no longer taste the Fennel. And while parents can't yet turn to their doctors to ask for this . Being jabbed with strange substances and experiencing shedding from those individuals has become a reality in this world we live in. [1] Specifically, it is used for treatment of first-stage African trypanosomiasis caused by Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense without involvement of central nervous system. Cat's claw, hailing from a woody vine in the Amazon rainforest, is another herb with spectacular antiviral properties. ", 20. ME/CFS is a multi-systemic neurological disease, distinct from chronic fatigue as a symptom. Pine needle tea (obviously nothing poisonous as most pine nuts (from all pine cones ) are edible but some are poisonous she was just covering her ass so to speak ppl have been makin this kinda tea for ages it has high vitamin c and has been used against scurvy for Mariners for 1000s of years, Do you know if the dandylion, star anise, fennel or pine needles have to be in tea or heated to release the suramin? These pannexin channel blockers will likely be synergistic with anti-purinergic drugs in helping to reset, reboot, and support the completion of the healing cycle when it becomes stuck in any of the stages of the CDR. The N/W/O and all their minions. Thats because I buy Fennel essential oil (100% pure, therapeutic grade) and drop a couple of drops into my bottle of water. Thankfully God has not left them and us comfortless, there is an antidote, Suramin, that Dr. Judy Mikovits and others speak about in this article, available in Pine Needle Tea you can make yourself. I have a 21 year old son with autism Many dont want to allow their bubble to burst as they feel so safe and secure tucked away inside there. Pure suramin is colorless when dissolved in water or saline as a 10% solution (100 mg/mL). Food Shortage Coming Soon, County Returns $1.2M NIH Funds & Confirms Vaxx is a Bioweapon, Protect Babies Thru Adults From Dioxin Toxicity w/ Adequate Vit C, DETOX Dioxin Air & Soil Exposure w/ Broccoli Sprouts For Pennies, Natures Penicillin: For Pneumonia, Earache, Flu, Bronchitis & More. Homeopathic remedies have been praised by advocates for use against viruses and routine ailments. [11], Less common side effects include extreme fatigue, ulcers in the mouth, and painful tender glands in the neck, armpits and groin. She was healthy and lived a long life taking this faithfully. [11], The molecular formula of suramin is C51H40N6O23S6. Do you think that Rheum Palmatum is the richest plant? Aug 12, 2017 . Consult your own doctor. 4. Suramin inhibits chikungunya virus replication through multiple mechanisms. Choose what fits your situation best. It is still early to say but maybe this will enter the top three interventions. JavaScript is disabled. You must log in or register to reply here. A lawn treated with Roundup would also have no grass, as well as no dandelions, no anything. Mayan's Secret Organic Black Cumin Seed Oil. Before you begin treatment with suramin, you and your doctor should . The synthesis of suramin was an extension of Paul Ehrlich's pioneering work that showed that certain chemical dyes were concentrated in microbial parasites like the trypanosomes that cause African . Based on this system, we have demonstrated that an aqueous extract from the Natural herb Prunella vulgaris (NhPV) displayed potent inhibitory effects on SCoV-2 SP (including SPG614 mutant) pseudotyped virus (SCoV-2-SP-PVs) mediated infections. "Suramin rapidly alters cellular tyrosine phosphorylation in prostate cancer cell lines. I love the way she says that they wouldnt be injecting people unless they already knew what could be done to reverse it. and this shows what Graphene oxide does to the blood of the vaccinated under the microscope: This protocol may mitigate damage in those with buyers remorse whove been injected with spike protein, graphene oxide, SM-102, and mRNA. Suramin is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 M). Its such a dreadful thing that they robbed us of such good food and have destroyed it by pasteurizing and homogenising. [7], Suramin is used for treatment of human sleeping sickness caused by trypanosomes. Repurposing suramin for the treatment of breast cancer lung metastasis with glycol chitosan-based nanoparticles. NAC (N-acetyl cysteine) accelerates detoxification and is . The goal will be to find synergistic therapies that can bring patients with chronic conditions through the stages of healing discussed above. Unfortunately, the importance of ATP and related metabolites in regulating the symptoms of disease and the stages of the healing cycle has only recently been recognized. I was excited by these findings too esp as I am also on the autism spectrum. Bumping this to see if anyone's benefited from high dose Kudzu, Good question, I don't have a good answer, though someone with more scientific knowledge than me could probably calculate it using the paper cited above, I'd be remiss if I didn't post this Kudzu precaution literature.

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